San Francisco Mixed Use Retail/Office

About this listing

The Cathedral Hill location is a strategic opportunity for commercial real estate investment that presents a compelling opportunity for real estate investors seeking stable, centrally located assets in San Francisco. Situated along major arteries like Van Ness Avenue and Geary Boulevard, the neighborhood offers excellent visibility, high traffic counts, and consistent demand driven by its proximity to healthcare, government, and cultural institutions.
The area’s commercial inventory is a mix of medical office buildings, mid-rise professional centers, ground-floor retail in residential complexes, and hotel assets—many had been built during the city’s mid-century boom and recently offered significant value-add or redevelopment potential. With the recent infrastructure upgrades along Van Ness (including BRT lanes and urban streetscape improvements), the corridor is poised for long-term appreciation and increased foot traffic.
The key demand drivers include Healthcare anchor tenants with major medical institutions like the new CPMC Campus, the San Francisco Towers, Kaiser Permanente and UCSF/Mount Zion all nearby, the area sees steady demand for medical office space and supporting services (labs, urgent care, outpatient clinics).
Cathedral Hill’s central location and accessibility make it attractive for boutique hotels and extended-stay lodging, especially given the nearby convention, civic, and cultural facilities.
Mixed-use development has taken place with underutilized lots and older properties along Geary and Van Ness which remain prime candidates for repositioning into mixed-use, combining residential, retail, or office, especially as city zoning evolves post-COVID to support more flexible land use.
Rental rates for commercial spaces in Cathedral Hill are typically lower than high-demand corridors like SOMA or the Financial District, but vacancy rates remain relatively tight due to the neighborhood’s niche positioning and local-serving tenant mix. Investors benefit from long-term tenants and lower turnover, making it attractive for buy-and-hold strategies with moderate cap rates and strong upside through renovation or repositioning.
With a location at the crossroads of multiple high profile neighborhoods, transit routes, dense housing, and institutional anchors, Cathedral Hill is a smart pick for commercial investors who see potential in San Francisco’s more under-the-radar but highly functional neighborhoods.
It’s great for people who want proximity to cultural spots and downtown, but without the full-on hustle of more tourist-heavy zones. It can feel a bit under-the-radar compared to neighborhoods like Hayes Valley or the Mission.

Located in the sought-after Cathedral Hill /Lower Pacific Heights neighborhoods
3,404 SF freestanding structure
Zoned NC-3: flexible for retail or office use
Strong market fundamentals and high foot traffic area

The property is positioned in the heart of one of San Francisco’s most desirable commercial districts, this 3,404 SF freestanding building presents a rare and compelling investment opportunity. Built in 1910, the property blends historic charm with modern potential, offering a versatile space ideal for retail or office use.
Zoned NC-3 (Neighborhood Commercial), the building’s flexible layout and zoning allow for a wide range of commercial applications, making it especially attractive to investors and owner-users alike. Its prominent location in the vibrant Lower Pacific Heights neighborhood ensures strong visibility and steady foot traffic, while the area’s continued growth enhances long-term value.
Currently the property is occupied by a street level convenience store with the upper level consisting of 6 private offices.
With its timeless architectural character and undeniable curb appeal, this property offers not just a place of business—but a distinctive presence in San Francisco’s thriving commercial landscape.
Outstanding opportunity with owner user potential or a straightforward investment in the densely populated Cathedral Hill neighborhood.